Technology Products Company Contact Us Home
Products
Overview
Brochure
Features
Technical Data
Videos
FAQ
 
 

Features


The Photoconductive Stimulation Device features.




Representation of the LED with stimulation properties depicted.



Feature List

  • Hippocampal/Cortical cultures are optimized for growth on silicon wafers


  • The photoconductive effect alters the conductivity of silicon with exposure to light


  • Illuminate as small an area as approximately 50 microns


  • Stimulation protocols can be from 0.1 Hz up to 100 Hz and approximately up to a 17 volt pulse across entire surface of wafer


  • Only illuminated neuron(s) depolarize on-demand


  • Activity can be detected by fluo4 or voltage sensitive dyes
  • Study cellular response by standard protocols or live imaging


  • Non-invasive, preserves cytoskeleton, physiologically benign


  • Cell specific (demonstrated by FM loading)


  • Concurrent electrophysiological recordings demonstrate high frequency stimulation possible


  • Stimulation can result in controlled synaptic and network remodeling


  • Networks formed have complex activity patterns

© Neurosilicon, 2009  |  Home | Technology | Products | Company | Contact Us